Kieran Culkin and All His Brothers Are Working Together for the First Time

Opening Night For "After Ashley" - After Party

(R-L) Actors Kieran Culkin and Macaulay Culkin attend the after party for the opening night of "After Ashley" on February 28, 2005 in New York City. (Photo by Peter Kramer/Getty Images)Photo: Peter Kramer / Getty Images Entertainment / Getty Images

For the first time ever, all five Culkin Brothers are working together on the same project. We're talkin' Macaulay, Kieran, Rory, Christian AND Shane!  

The project is an animated series for Prime Video called "The Second Best Hospital in the Galaxy".

Kieran voices a regular character, but his brothers are only guest-starring on a single episode as . . . his brothers. They're some kind of species of alien bird people.

The show is about, quote, "intergalactically renowned surgeons who tackle anxiety-eating parasites, illegal time loops, and deep-space STIs." It hits Prime on Friday.

Check out a preview of the Culkins at work here . . . and watch a trailer for the series here:

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